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A Response from Natalie Northrup at MIT: Not particularly well, but there are a few strategies I use. Most often, I let myself mentally envision what my life could look like under a bunch of the possible outcomes – which most often allows me to see that I can really be okay even if uncertain events throw me somewhere unexpected. I also strictly block free time into my week, so even though I could always be working to address the uncertainty I give myself time to be happy and human in the here and now without feeling guilty.